Papers
Influence Of Additives On The Electrostatic Charge Build-Up Of Excipients - 2022
Neveu A, Patel D, Francqui F, “Influence of Additives on the Electrostatic Charge Build-Up of Excipients”. ONdrugDelivery, Issue 135 (Jul 2022), pp 12–15.
Aurélien Neveu, PhD, Head of Laboratory and Applications at Granutools, Devang Patel, PhD, Senior Research Scientist at Natoli Engineering Company, and Filip Francqui, Managing Director at Granutools, present a study investigating the influence of additives on the tribocharging behaviour of two excipients using Granutools’ GranuCharge instrument.
Good flowability is a key factor for numerous powder processes, with the consistency of the flow directly related to the final product quality. However, when a powder flows, the frictional contact between the particles creates electrostatic charges via the triboelectric effect. This charge build up induces an increase in the strength of the electrostatic cohesive interactions that contribute to the global cohesiveness of the powder and therefore a decrease in its flowability properties.