Unravel the mystery of powder caking in industries like food and pharmaceuticals. Prolonged storage triggers aggregation, unveiling a tale of quality challenges and intrigue.
For each experiment with the GranuPack, 500 taps were applied to the sample with a taps frequency of 1Hz and the measurement cell free-fall was 1 mm (∝ tap energy). The powder mass is recorded before each experiment...
The tap density test / tap test tool is a usefull compressibility tool commonly used in quality control and R&D for developing new formulations. This test can be used for calculating the Hausner ratio (Hr) or the Carr index value...
The excipient used during this application note is called Pharmatose 200M and was provided by DFE Pharma. This is a pharmaceutical α-lactose monohydrate and it is mechanically milled...
The main purpose of this application note is to provide information about the measurements reproducibility with the GranuFlow and to show some examples about what is it able to offer...
Electrostatic charges are created inside a powder during a flow. This apparition of electric charges is due to the triboelectric effect, which is a charge exchange at the contact between two solids...
When a powder is poured onto a surface, a heap is formed. It is well known that both the repose angle and the heap shape strongly depend on grain properties. In particular, a cohesive powder forms an irregular heap while a non-cohesive powder forms a regular conical heap.
The GranuFlow is a straightforward powder flowability measurement device composed of a silo with different apertures associated with a dedicated electronic balance to measure the flowrate...
One of the biggest advantages of the Dry Powder Inhaler (DPI) is that it allows a better preservation of the formulation due to the absence of water in the formulation...
Dry powder inhalers (DPI) offer many advantages to the respiratory administration. They show a targeted effect (they do not diffuse towards inappropriate sites in the body), they attain higher concentrations in the lungs resulting in a considerable reduced drug dose.