Pharmaceutical

On the inherent correlation between the fluidization and flow properties of cohesive powders

P. Christian van der Sande, Kaiqiao Wu, Rens Kamphorst, Evert C. Wagner, Gabrie M. H. Meesters, J. Ruud van Ommen, On the inherent correlation between the fluidization and flow properties of cohesive powders, AIChE Journal, 26 December 2024.

How to evaluate powder caking with GranuPack

Powder caking is important for industrial applications. Learn how the GranuPack can measure the caking and investigate it thanks to this protocol.

GranuFlow: A Primer on Powder Flow Testing and Pharmacopeial Standards

In this study, we put the emphasis on the significance of the GranuFlow and how it elevates the standards of pharmaceutical powder testing.

Improvement of a pharmaceutical powder mixing process in a tote blender via DEM simulations

B. Benque, L. Orefice, T. Forgber, M. Habeler, B. Schmid, J. Remmelgas, J. Khinast, Improvement of a pharmaceutical powder mixing process in a tote blender via DEM simulations, International Journal of Pharmaceutics, Volume 658, 2024, 124224, ISSN 0378-5173.

Measuring permeability and flowability of powders at various packing fractions

Lupo M, Neveu A, Gemine T, Francqui F, Lumay G, “Measuring permeability and flowability of powders at various packing fractions”. Particuology, 4 April 2024

Investigating powder caking in a short time with the GranuPack High Temperature

Unravel the mystery of powder caking in industries like food and pharmaceuticals. Prolonged storage triggers aggregation, unveiling a tale of quality challenges and intrigue.

A novel methodology for data analysis of dynamic angle of repose tests and powder flow classification

Orefice L, Remmelgas J, Neveu A, Francqui F, Khinast J.G, “A novel methodology for data analysis of dynamic angle of repose tests and powder flow classification”. Powder Technology, Volume 435, 15 February 2024, 119425

Powder Permeability Measurements at Low Consolidation Conditions

In this blog article, we explain what powder permeability is and its importance with the GranuPack Permeability.

Powder Characterisation for Pharmaceuticals: Beyond Standards

Neveu A, Lupo M, Francqui F, “Powder Characterisation for Pharmaceuticals: Beyond Standards”. ONdrugDelivery, Issue 148 (May/June 2023), pp 16–19.

Powder Characterization For DPI Performance In Capsule-Based Inhalers

Pillitteri S, Neveu A, Zellnitz-Neugebauer S, “Powder Characterisation for DPI Performance in Capsule-Based Inhalers”. ONdrugDelivery, Issue 140 (Nov 2022), pp 77–81.

Why is powder caking an important phenomenon for industrial applications?

Learn more about powder caking with our new blog article.

Measuring powder air permeability with GranuPack

The GranuPack instrument can be equipped with a measurement cell allowing a permeability measurement. This measurement characterizing the ability of air to pass through a powder is of crucial importance for many applications.

Influence Of Additives On The Electrostatic Charge Build-Up Of Excipients - 2022

Neveu A, Patel D, Francqui F, “Influence of Additives on the Electrostatic Charge Build-Up of Excipients”. ONdrugDelivery, Issue 135 (Jul 2022), pp 12–15.

Impact of Powder Properties on the Rheological Behavior of Excipients - 2021

P. H. M. Janssen, S. Depaifve, A. Neveu, F. Francqui, B. H. J. Dickhoff
Pharmaceutics 2021, 13(8), 1198; https://doi.org/10.3390/pharmaceutics13081198

Flowing Properties Of Spray-Dried Powders Before And After Granulation - 2021

G. Lumay, L. De Smet, F. Van der Gucht & F. Francqui

Packing Dynamics of Powders At High Temperature - 2021

Aurélien Neveu[1], Filip Francqui[1] and Geoffroy Lumay[2], EPJ Web of Conferences 249, 12001 (2021)

1 GranuTools, Awans, Belgium
2 GRASP Laboratory, CESAM research unit, University of Liège, Belgium

Rotating drum measurement in the pharmaceutical industry

This article will explain how the rotating drum measurement and the GranuDrum can be used in the pharmaceutical industry. What are the benefits of using new methods and how would you know if one test is relevant or not.

Characterization of lactose powders for DPI applications - 2021

A. Neveu, M. Crowley, T. McGorisk, ONdrugDelivery, Issue N°119

Influence Of the Drug Load On Pharmaceutical Blends Processability

For each experiment with the GranuPack, 500 taps were applied to the sample with a taps frequency of 1Hz and the measurement cell free-fall was 1 mm (∝ tap energy). The powder mass is recorded before each experiment...

Loss-In-Weight Feeding, Powder Flow And Electrostatic Evaluation For Direct Compression

C. Allenspach, P. Timmins, G. Lumay, J. Holman, T.Minko, International Journal of Pharmaceutics Volume 596, 1 March 2021, 120259